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Daclizumab, a humanised monoclonal antibody to the interleukin 2 receptor (CD25), for the treatment of moderately to severely active ulcerative colitis: a randomised, double blind, placebo controlled, dose ranging trial

BACKGROUND: An uncontrolled pilot study demonstrated that daclizumab, a humanised monoclonal antibody to the interleukin 2 receptor (CD25), might be effective for the treatment of active ulcerative colitis. METHODS: A randomised, double blind, placebo controlled trial was conducted to evaluate the e...

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Autori principali: Van Assche, G, Sandborn, W J, Feagan, B G, Salzberg, B A, Silvers, D, Monroe, P S, Pandak, W M, Anderson, F H, Valentine, J F, Wild, G E, Geenen, D J, Sprague, R, Targan, S R, Rutgeerts, P, Vexler, V, Young, D, Shames, R S
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMJ Group 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1860086/
https://ncbi.nlm.nih.gov/pubmed/16603634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2005.089854
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