Fontolizumab, a humanised anti‐interferon γ antibody, demonstrates safety and clinical activity in patients with moderate to severe Crohn's disease

INTRODUCTION: Interferon γ is a potent proinflammatory cytokine implicated in the inflammation of Crohn's disease (CD). We evaluated the safety and efficacy of fontolizumab, a humanised anti‐interferon γ antibody, in patients with moderate to severe CD. METHODS: A total of 133 patients with Cro...

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Dettagli Bibliografici
Autori principali: Hommes, D W, Mikhajlova, T L, Stoinov, S, Štimac, D, Vucelic, B, Lonovics, J, Zákuciová, M, D'Haens, G, Van Assche, G, Ba, S, Lee, S, Pearce, T
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMJ Group 2006
Soggetti:
Inflammatory Bowel Disease
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1856291/
https://ncbi.nlm.nih.gov/pubmed/16507585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2005.079392
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