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Adenovirus-mediated gene transfer into normal rabbit arteries results in prolonged vascular cell activation, inflammation, and neointimal hyperplasia.

Adenovirus vectors are capable of high efficiency in vivo arterial gene transfer, and are currently in use as therapeutic agents in animal models of vascular disease. However, despite substantial data on the ability of viruses to cause vascular inflammation and proliferation, and the presence in cur...

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Dettagli Bibliografici
Autori principali: Newman, K D, Dunn, P F, Owens, J W, Schulick, A H, Virmani, R, Sukhova, G, Libby, P, Dichek, D A
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1995
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC186007/
https://ncbi.nlm.nih.gov/pubmed/8675667
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