Adenovirus-Mediated Gene Transfer of microRNA-21 Sponge Inhibits Neointimal Hyperplasia in Rat Vein Grafts

Background:Vein graft failure due to neointimal hyperplasia remains an important and unresolved complication of cardiovascular surgery. microRNA-21 (miR-21) plays a major role in regulating vascular smooth muscle cell (VSMC) proliferation and phenotype transformation. Thus, the purpose of this study...

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Bibliografiska uppgifter
I publikationen:Int J Biol Sci
Huvudupphovsmän: Wang, Xiao-Wen, Zhang, Cheng, Lee, Kai-Chuen, He, Xiang-Jun, Lu, Zhi-Qian, Huang, Chun, Wu, Qing-Chen
Materialtyp: Artigo
Språk:Inglês
Publicerad: Ivyspring International Publisher 2017
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5666529/
https://ncbi.nlm.nih.gov/pubmed/29104497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.20254
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