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Genomic abnormalities of the murine model of Fabry disease after disease-related perturbation, a systems biology approach

Fabry disease is a disorder of α-d-galactosyl-containing glycolipids resulting from a deficiency of α-galactosidase A. Patients have a poorly understood vascular dysregulation. We hypothesized that disease-related perturbation by using enzyme replacement therapy in the murine model of Fabry disease...

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Huvudupphovsmän: Moore, David F., Gelderman, Monique P., Ferreira, Paulo A., Fuhrmann, Steven R., Yi, Haiqing, Elkahloun, Abdel, Lix, Lisa M., Brady, Roscoe O., Schiffmann, Raphael, Goldin, Ehud
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2007
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1859990/
https://ncbi.nlm.nih.gov/pubmed/17470787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0701991104
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