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Establishment and Characterization of Fabry Disease Endothelial Cells with an Extended Lifespan

Fabry disease is an inborn error of glycosphingolipid catabolism resulting from a deficiency of lysosomal enzyme α-galactosidase A. The major clinical manifestations of the disease, such as stroke, cardiac dysfunction, and renal impairment, are thought to be caused by vasculopathy due to progressive...

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Autores principales: Shen, Jin-Song, Meng, Xing-Li, Schiffmann, Raphael, Brady, Roscoe O., Kaneski, Christine R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2063578/
https://ncbi.nlm.nih.gov/pubmed/17644384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2007.06.003
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