Individuals homozygous for the age-related macular degeneration risk-conferring variant of complement factor H have elevated levels of CRP in the choroid

Polymorphisms in the complement factor H gene (CFH) are associated with a significantly increased risk for, or protection against, the development of age-related macular degeneration (AMD). The most documented risk-conferring single-nucleotide polymorphism results in a tyrosine-to-histidine substitu...

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Detalhes bibliográficos
Main Authors: Johnson, P. T., Betts, K. E., Radeke, M. J., Hageman, G. S., Anderson, D. H., Johnson, L. V.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1859950/
https://ncbi.nlm.nih.gov/pubmed/17079491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0606234103
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