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Astrocyte elevated gene-1 (AEG-1) is a target gene of oncogenic Ha-ras requiring phosphatidylinositol 3-kinase and c-Myc

It is well established that Ha-ras and c-myc genes collaborate in promoting transformation, tumor progression, and metastasis. However, the precise mechanism underlying this cooperation remains unclear. In the present study, we document that astrocyte elevated gene-1 (AEG-1) is a downstream target m...

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Autori principali: Lee, Seok-Geun, Su, Zao-Zhong, Emdad, Luni, Sarkar, Devanand, Fisher, Paul B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1859939/
https://ncbi.nlm.nih.gov/pubmed/17088530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0608386103
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