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Evidence for preferential Ig gene usage and differential TdT and exonuclease activities in human naïve and memory B cells

Memory B cells and the antibodies they encode are important for protective immunity against infectious pathogens. Characterization of naïve and memory B cell antibody repertoires will elucidate the molecular basis for the generation of antibody diversity in human B cells and the optimization of anti...

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Библиографические подробности
Главные авторы: Tian, Cuixia, Luskin, Grace K., Dischert, Kevin M., Higginbotham, James N., Shepherd, Bryan E., Crowe, James E.
Формат: Artigo
Язык:Inglês
Опубликовано: 2006
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1859862/
https://ncbi.nlm.nih.gov/pubmed/17196657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2006.11.020
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