Endogenous production of interleukin 15 by activated human monocytes is critical for optimal production of interferon-gamma by natural killer cells in vitro.

Natural killer (NK) cells are large granular lymphocytes that constitutively express functional IL-2 receptors. We have shown that recombinant human IL-15 uses the IL-2 receptor to activate human NK cells and can synergize with recombinant human IL-12 to stimulate NK cell production of IFN-gamma in...

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Main Authors: Carson, W E, Ross, M E, Baiocchi, R A, Marien, M J, Boiani, N, Grabstein, K, Caligiuri, M A
格式: Artigo
語言:Inglês
出版: 1995
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC185961/
https://ncbi.nlm.nih.gov/pubmed/8675621
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