Endogenous production of interleukin 15 by activated human monocytes is critical for optimal production of interferon-gamma by natural killer cells in vitro.

Natural killer (NK) cells are large granular lymphocytes that constitutively express functional IL-2 receptors. We have shown that recombinant human IL-15 uses the IL-2 receptor to activate human NK cells and can synergize with recombinant human IL-12 to stimulate NK cell production of IFN-gamma in...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Carson, W E, Ross, M E, Baiocchi, R A, Marien, M J, Boiani, N, Grabstein, K, Caligiuri, M A
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1995
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185961/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8675621/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118321
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