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Synthesis and biological activity of tripeptidyl polyoxins as antifungal agents.

Three tripeptidyl polyoxins were synthesized and found to inhibit Candida albicans. Compared with the naturally occurring polyoxin D, the three synthetic polyoxins had little effect on chitin synthetase when assayed with a C. albicans membrane preparation. However, all the compounds inhibited growth...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Naider, F, Shenbagamurthi, P, Steinfeld, A S, Smith, H A, Boney, C, Becker, J M
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1983
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185943/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6362556/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.24.5.787
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