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Synthesis and biological activity of tripeptidyl polyoxins as antifungal agents.

Three tripeptidyl polyoxins were synthesized and found to inhibit Candida albicans. Compared with the naturally occurring polyoxin D, the three synthetic polyoxins had little effect on chitin synthetase when assayed with a C. albicans membrane preparation. However, all the compounds inhibited growth...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Naider, F, Shenbagamurthi, P, Steinfeld, A S, Smith, H A, Boney, C, Becker, J M
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1983
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185943/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6362556/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.24.5.787
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