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Mechanical strain of rat vascular smooth muscle cells is sensed by specific extracellular matrix/integrin interactions.

Cyclic mechanical strain (1 Hz) causes a mitogenic response in neonatal rat vascular smooth muscle cells due to production and secretion of PDGF. In this study, the mechanism for sensing mechanical strain was investigated. Silicone elastomer strain plates were coated at varying densities with elasti...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Principais autores: Wilson, E, Sudhir, K, Ives, H E
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1995
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185888/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7593624/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118293
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