Mechanical strain of rat vascular smooth muscle cells is sensed by specific extracellular matrix/integrin interactions.

Cyclic mechanical strain (1 Hz) causes a mitogenic response in neonatal rat vascular smooth muscle cells due to production and secretion of PDGF. In this study, the mechanism for sensing mechanical strain was investigated. Silicone elastomer strain plates were coated at varying densities with elasti...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Wilson, E, Sudhir, K, Ives, H E
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185888/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7593624/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118293
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