TXNIP Regulates Peripheral Glucose Metabolism in Humans

BACKGROUND: Type 2 diabetes mellitus (T2DM) is characterized by defects in insulin secretion and action. Impaired glucose uptake in skeletal muscle is believed to be one of the earliest features in the natural history of T2DM, although underlying mechanisms remain obscure. METHODS AND FINDINGS: We c...

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Autores principales: Parikh, Hemang, Carlsson, Emma, Chutkow, William A, Johansson, Lovisa E, Storgaard, Heidi, Poulsen, Pernille, Saxena, Richa, Ladd, Christine, Schulze, P. Christian, Mazzini, Michael J, Jensen, Christine Bjørn, Krook, Anna, Björnholm, Marie, Tornqvist, Hans, Zierath, Juleen R, Ridderstråle, Martin, Altshuler, David, Lee, Richard T, Vaag, Allan, Groop, Leif C, Mootha, Vamsi K
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1858708/
https://ncbi.nlm.nih.gov/pubmed/17472435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0040158
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