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TXNIP Regulates Peripheral Glucose Metabolism in Humans

BACKGROUND: Type 2 diabetes mellitus (T2DM) is characterized by defects in insulin secretion and action. Impaired glucose uptake in skeletal muscle is believed to be one of the earliest features in the natural history of T2DM, although underlying mechanisms remain obscure. METHODS AND FINDINGS: We c...

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Bibliographische Detailangaben
Hauptverfasser: Parikh, Hemang, Carlsson, Emma, Chutkow, William A, Johansson, Lovisa E, Storgaard, Heidi, Poulsen, Pernille, Saxena, Richa, Ladd, Christine, Schulze, P. Christian, Mazzini, Michael J, Jensen, Christine Bjørn, Krook, Anna, Björnholm, Marie, Tornqvist, Hans, Zierath, Juleen R, Ridderstråle, Martin, Altshuler, David, Lee, Richard T, Vaag, Allan, Groop, Leif C, Mootha, Vamsi K
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1858708/
https://ncbi.nlm.nih.gov/pubmed/17472435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0040158
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