TXNIP Regulates Peripheral Glucose Metabolism in Humans

BACKGROUND: Type 2 diabetes mellitus (T2DM) is characterized by defects in insulin secretion and action. Impaired glucose uptake in skeletal muscle is believed to be one of the earliest features in the natural history of T2DM, although underlying mechanisms remain obscure. METHODS AND FINDINGS: We c...

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Hlavní autoři: Parikh, Hemang, Carlsson, Emma, Chutkow, William A, Johansson, Lovisa E, Storgaard, Heidi, Poulsen, Pernille, Saxena, Richa, Ladd, Christine, Schulze, P. Christian, Mazzini, Michael J, Jensen, Christine Bjørn, Krook, Anna, Björnholm, Marie, Tornqvist, Hans, Zierath, Juleen R, Ridderstråle, Martin, Altshuler, David, Lee, Richard T, Vaag, Allan, Groop, Leif C, Mootha, Vamsi K
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2007
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1858708/
https://ncbi.nlm.nih.gov/pubmed/17472435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0040158
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