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Conformational study of the protegrin-1 (PG-1) dimer interaction with lipid bilayers and its effect

BACKGROUND: Protegrin-1 (PG-1) is known as a potent antibiotic peptide; it prevents infection via an attack on the membrane surface of invading microorganisms. In the membrane, the peptide forms a pore/channel through oligomerization of multiple subunits. Recent experimental and computational studie...

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Autori principali: Jang, Hyunbum, Ma, Buyong, Nussinov, Ruth
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1858697/
https://ncbi.nlm.nih.gov/pubmed/17407565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-7-21
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