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YRA1 autoregulation requires nuclear export and cytoplasmic Edc3p-mediated degradation of its pre-mRNA

Autoregulatory loops often provide precise control of the level of expression of specific genes that encode key regulatory proteins. Here we have defined a pathway by which Yra1p, a yeast mRNA export factor, controls its own expression. We show that YRA1 exon1 sequences in cis and Yra1p in trans inh...

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Hlavní autoři: Dong, Shuyun, Li, Chunfang, Zenklusen, Daniel, Singer, Robert H., Jacobson, Allan, He, Feng
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1858660/
https://ncbi.nlm.nih.gov/pubmed/17317628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.01.012
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