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Expression of the essential mRNA export factor Yra1p is autoregulated by a splicing-dependent mechanism.

Recent evidence supports the idea that pre-mRNA splicing and mRNA export are mechanistically coupled. In metazoans, this process appears to be mediated by a multicomponent complex, which associates with the spliced RNA upstream of the exon-exon junction. One of these components (Aly/REF) has a homol...

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Autors principals: Preker, Pascal J, Kim, Karen S, Guthrie, Christine
Format: Artigo
Idioma:Inglês
Publicat: 2002
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370319/
https://ncbi.nlm.nih.gov/pubmed/12212852
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