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An intron in the YRA1 gene is required to control Yra1 protein expression and mRNA export in yeast

Yra1p is an essential and conserved mRNA export factor in yeast. Strikingly, removal of the intron from YRA1 causes a dominant-negative growth phenotype and a concomitant inhibition of mRNA export. However, both defects are neutralized by replacement of the intron of YRA1 by a different intron. Sign...

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Autori principali: Rodríguez-Navarro, Susana, Sträßer, Katja, Hurt, Ed
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1084104/
https://ncbi.nlm.nih.gov/pubmed/11964382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kvf091
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