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p53 gene mutations are common in uterine serous carcinoma and occur early in their pathogenesis.

Uterine serous carcinoma (USC) is an uncommon but aggressive type of endometrial cancer associated with rapid progression of disease and a poor prognosis. Both USC and its recently described putative precursor, endometrial intraepithelial carcinoma (EIC), demonstrate strong p53 overexpression by imm...

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Main Authors: Tashiro, H., Isacson, C., Levine, R., Kurman, R. J., Cho, K. R., Hedrick, L.
Formato: Artigo
Idioma:Inglês
Publicado: 1997
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1858541/
https://ncbi.nlm.nih.gov/pubmed/9006334
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