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Gain of chromosome 17 is the most frequent abnormality detected in neuroblastoma by comparative genomic hybridization.

Neuroblastoma behavior is variable and outcome partially depends on genetic factors. However, tumors that lack high-risk factors such as MYCN amplification or 1p deletion may progress, possibly due to other genetic aberrations. Comparative genomic hybridization summarizes DNA copy number abnormaliti...

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Bibliographic Details
Main Authors: Plantaz, D., Mohapatra, G., Matthay, K. K., Pellarin, M., Seeger, R. C., Feuerstein, B. G.
Format: Artigo
Language:Inglês
Published: 1997
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1858505/
https://ncbi.nlm.nih.gov/pubmed/9006325
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