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Organ-site dependence for the production of urokinase-type plasminogen activator and metastasis by human renal cell carcinoma cells.

We examined the role of urokinase-type plasminogen activator (u-PA) in the metastasis of the human renal cell carcinoma (HRCC) implanted in athymic nude mice. Cells from a HRCC KG-2 line were implanted in orthotopic (kidney) and ectopic (subcutaneous) organs. The KG-2 cells implanted in the kidney p...

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Autors principals: Gohji, K., Nakajima, M., Boyd, D., Dinney, C. P., Bucana, C. D., Kitazana, S., Kamidono, S., Fidler, I. J.
Format: Artigo
Idioma:Inglês
Publicat: 1997
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1858342/
https://ncbi.nlm.nih.gov/pubmed/9403716
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