Presenilin-1-immunoreactive neurons are preserved in late-onset Alzheimer's disease.

Recent studies have suggested that missense mutations in the presenilin-1 gene are causally related to the majority of familial early-onset Alzheimer's disease (AD). To examine the possible involvement of presenilin-1 in late-onset sporadic AD, a quantitative analysis of its distribution in the...

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Autors principals: Giannakopoulos, P., Bouras, C., Kövari, E., Shioi, J., Tezapsidis, N., Hof, P. R., Robakis, N. K.
Format: Artigo
Idioma:Inglês
Publicat: 1997
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1858297/
https://ncbi.nlm.nih.gov/pubmed/9033258
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