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Biotin-labeled hairpin oligonucleotides: probes to detect double-strand breaks in DNA in apoptotic cells.

Hairpin oligonucleotides were synthesized with stems ending in a double-stranded structure, which can be ligated to double-strand breaks in DNA, and with loops that contain nucleotides modified by the attachment of biotin. These probes specifically and sensitively detect double-strand breaks in apop...

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Bibliografske podrobnosti
Main Authors: Didenko, V. V., Tunstead, J. R., Hornsby, P. J.
Format: Artigo
Jezik:Inglês
Izdano: 1998
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1858232/
https://ncbi.nlm.nih.gov/pubmed/9546350
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