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APC mutation and the crypt cycle in murine and human intestine.

Dysplastic colon adenomas are thought to arise from growth of clones of APC -/- colonic epithelial cells. Isolated clusters of dysplastic crypts are often observed in patients with familial adenomatous polyposis. These patients have genotype APC +/-, and the clusters of dysplastic crypts (called mic...

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Detalhes bibliográficos
Main Authors: Bjerknes, M., Cheng, H., Hay, K., Gallinger, S.
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1857872/
https://ncbi.nlm.nih.gov/pubmed/9060821
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