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Frequent p16INK4 (MTS1) gene inactivation in testicular germ cell tumors.

The molecular mechanisms responsible for the development of testicular germ cell tumors (GCTs) have not as yet been elucidated. The aim of the present study was to determine whether genetic alterations of p16INK4 (MTS1) and/or cyclin-dependent kinase 4 (CDK4) occur in the genesis of these tumors. We...

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Autores principales: Chaubert, P., Guillou, L., Kurt, A. M., Bertholet, M. M., Metthez, G., Leisinger, H. J., Bosman, F., Shaw, P.
Formato: Artigo
Lenguaje:Inglês
Publicado: 1997
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1857830/
https://ncbi.nlm.nih.gov/pubmed/9284835
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