Coping with Viral Diversity in HIV Vaccine Design

The ability of human immunodeficiency virus type 1 (HIV-1) to develop high levels of genetic diversity, and thereby acquire mutations to escape immune pressures, contributes to the difficulties in producing a vaccine. Possibly no single HIV-1 sequence can induce sufficiently broad immunity to protec...

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Autors principals: Nickle, David C, Rolland, Morgane, Jensen, Mark A, Pond, Sergei L. Kosakovsky, Deng, Wenjie, Seligman, Mark, Heckerman, David, Mullins, James I, Jojic, Nebojsa
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2007
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1857809/
https://ncbi.nlm.nih.gov/pubmed/17465674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.0030075
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