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Constitutive activation of different Jak tyrosine kinases in human T cell leukemia virus type 1 (HTLV-1) tax protein or virus-transformed cells.

HTLV-1 infection causes an adult T cell leukemia in humans. The viral encoded protein tax, is thought to play an important role in oncogenesis. Our previous data obtained from a tax transgenic mouse model revealed that tax transforms mouse fibroblasts but not thymocytes, despite comparable levels of...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Principais autores: Xu, X, Kang, S H, Heidenreich, O, Okerholm, M, O'Shea, J J, Nerenberg, M I
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1995
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185780/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7657825/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118193
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