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Specificity of prohormone convertase endoproteolysis of progastrin in AtT-20 cells.

Biologically active peptide hormones are synthesized from larger precursor proteins by a variety of posttranslational processing reactions. Endoproteolytic cleavage at the Lys74-Lys75 dibasic processing site of progastrin is the major determinant for the relative distribution of gastrin heptadecapep...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Principais autores: Dickinson, C J, Sawada, M, Guo, Y J, Finniss, S, Yamada, T
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1995
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185765/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7657815/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118178
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