Specificity of prohormone convertase endoproteolysis of progastrin in AtT-20 cells.

Biologically active peptide hormones are synthesized from larger precursor proteins by a variety of posttranslational processing reactions. Endoproteolytic cleavage at the Lys74-Lys75 dibasic processing site of progastrin is the major determinant for the relative distribution of gastrin heptadecapep...

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Pubblicato in:	J Clin Invest
Autori principali:	Dickinson, C J, Sawada, M, Guo, Y J, Finniss, S, Yamada, T
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1995
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185765/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7657815/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118178
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