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Rapid transcriptional activation and early mRNA turnover of brain natriuretic peptide in cardiocyte hypertrophy. Evidence for brain natriuretic peptide as an "emergency" cardiac hormone against ventricular overload.

We previously demonstrated that brain natriuretic peptide (BNP) is a cardiac hormone mainly produced in the ventricle, while the major production site of atrial natriuretic peptide (ANP) is the atrium. To assess the pathophysiological role of BNP in ventricular overload, we have examined the gene ex...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Nakagawa, O, Ogawa, Y, Itoh, H, Suga, S, Komatsu, Y, Kishimoto, I, Nishino, K, Yoshimasa, T, Nakao, K
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185749/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7657802/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118162
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