Rapid transcriptional activation and early mRNA turnover of brain natriuretic peptide in cardiocyte hypertrophy. Evidence for brain natriuretic peptide as an "emergency" cardiac hormone against ventricular overload.

We previously demonstrated that brain natriuretic peptide (BNP) is a cardiac hormone mainly produced in the ventricle, while the major production site of atrial natriuretic peptide (ANP) is the atrium. To assess the pathophysiological role of BNP in ventricular overload, we have examined the gene ex...

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Detalles Bibliográficos

Publicado en:	J Clin Invest
Autores principales:	Nakagawa, O, Ogawa, Y, Itoh, H, Suga, S, Komatsu, Y, Kishimoto, I, Nishino, K, Yoshimasa, T, Nakao, K
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Clinical Investigation 1995
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185749/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7657802/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118162
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