Tissue inhibitor of metalloproteinase‐3 differentially binds to components of Bruch's membrane

BACKGROUND: Sorsby's fundus dystrophy (SFD) is caused by mutations in tissue inhibitor of metalloproteinase (TIMP)‐3 and, with the exception of early onset, is similar to age‐related macular degeneration. The pathological features of this condition relate to the accumulation of TIMP‐3 in Bruch&...

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Detalhes bibliográficos
Main Authors: Majid, M A, Smith, V A, Matthews, F J, Newby, A C, Dick, A D
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2006
Assuntos:
Laboratory Science - Extended Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1857436/
https://ncbi.nlm.nih.gov/pubmed/16837541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bjo.2006.097246
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