Tissue inhibitor of metalloproteinase‐3 differentially binds to components of Bruch's membrane

BACKGROUND: Sorsby's fundus dystrophy (SFD) is caused by mutations in tissue inhibitor of metalloproteinase (TIMP)‐3 and, with the exception of early onset, is similar to age‐related macular degeneration. The pathological features of this condition relate to the accumulation of TIMP‐3 in Bruch&...

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Bibliografiske detaljer
Main Authors: Majid, M A, Smith, V A, Matthews, F J, Newby, A C, Dick, A D
Format: Artigo
Sprog:Inglês
Udgivet: BMJ Group 2006
Fag:
Laboratory Science - Extended Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1857436/
https://ncbi.nlm.nih.gov/pubmed/16837541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bjo.2006.097246
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