Loading...

Fluorous synthesis of disubstituted pyrimidines

The fluorous synthesis of disubstituted pyrimidines is carried out by attaching 2,4-dichloro-6-methylpyrimidine with 1H,1H,2H,2H-perfluorodecanethiol. The tagged substrate is substituted with 3-(trifluoromethyl)pyrazole followed by thioether oxidation and tag displacement with amines and thiols. The...

Full description

Saved in:
Bibliographic Details
Main Author: Zhang, Wei
Format: Artigo
Language:Inglês
Published: 2003
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1857353/
https://ncbi.nlm.nih.gov/pubmed/12659561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol027469e
Tags: Add Tag
No Tags, Be the first to tag this record!