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Fluorous synthesis of disubstituted pyrimidines

The fluorous synthesis of disubstituted pyrimidines is carried out by attaching 2,4-dichloro-6-methylpyrimidine with 1H,1H,2H,2H-perfluorodecanethiol. The tagged substrate is substituted with 3-(trifluoromethyl)pyrazole followed by thioether oxidation and tag displacement with amines and thiols. The...

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Bibliografiska uppgifter
Huvudupphovsman: Zhang, Wei
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2003
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1857353/
https://ncbi.nlm.nih.gov/pubmed/12659561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol027469e
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