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Fluorous Synthesis of Hydantoins and Thiohydantoins

[Image: see text] A fluorous synthesis of hydantoins is introduced. The reaction of perfluoroalkyl (Rfh)-tagged amino esters with an isocyanate is followed by the cyclization of ureas and simultaneous cleavage of the fluorous tag to afford hydantoins. The product purification is performed by solid-p...

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Detalhes bibliográficos
Main Authors: Zhang, Wei, Lu, Yimin
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1894909/
https://ncbi.nlm.nih.gov/pubmed/12841779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol034854a
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