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Steroid requirements for regulation of the α4 subunit of the GABA(A) receptor in an in vitro model

The α4 subunit of the GABA(A) receptor (GABAR) has relatively low expression in the CNS, but is increased in vivo following 48 h administration of the GABA-modulatory steroid 3α-OH-5α[β]-pregnan-20-one (THP or [allo]pregnanolone) to female rats. The purpose of the following study was to determine th...

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Detalhes bibliográficos
Main Authors: Zhou, Xiangping, Smith, Sheryl S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1857280/
https://ncbi.nlm.nih.gov/pubmed/17081691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2006.10.018
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