Activity of tunicamycin against Trypanosoma brucei in vitro and in vivo.

Tunicamycin, a specific inhibitor of glycoprotein biosynthesis, was evaluated for activity and chemotherapeutic potential against Trypanosoma brucei in vitro and in vivo. The inhibition of parasite incorporation of two radiolabeled macromolecular precursors, [methyl-3H]thymidine and D-[2-3H]mannose,...

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Detalles Bibliográficos

Publicado en:	Antimicrob Agents Chemother
Principais autores:	Casero, R A, Porter, C W, Bernacki, R J
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 1982
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185711/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7159066/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.22.6.1008
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