In vitro assessment of 2-acetylpyridine thiosemicarbazones against chloroquine-resistant Plasmodium falciparum.

A series of 2-acylpyridine thiosemicarbazones was evaluated in vitro against a chloroquine-resistant Plasmodium falciparum strain. Antimalarial activity was assessed by the inhibition of uptake of [G-3H]hypoxanthine by the parasites. Among the mono- and disubstituted derivatives tested, 13 of 17 had...

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Hauptverfasser: Lambros, C, Childs, G E, Notsch, J D, Scovill, J P, Klayman, D L, Davidson, D E
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1982
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC185705/
https://ncbi.nlm.nih.gov/pubmed/6760808
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