In vitro assessment of 2-acetylpyridine thiosemicarbazones against chloroquine-resistant Plasmodium falciparum.

A series of 2-acylpyridine thiosemicarbazones was evaluated in vitro against a chloroquine-resistant Plasmodium falciparum strain. Antimalarial activity was assessed by the inhibition of uptake of [G-3H]hypoxanthine by the parasites. Among the mono- and disubstituted derivatives tested, 13 of 17 had...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Lambros, C, Childs, G E, Notsch, J D, Scovill, J P, Klayman, D L, Davidson, D E
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1982
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185705/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6760808/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.22.6.981
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