Prediction of antitumour necrosis factor clinical efficacy by real‐time visualisation of apoptosis in patients with Crohn's disease

BACKGROUND: The human anti‐tumour necrosis factor (TNF) antibody infliximab binds to the membrane TNF and subsequently induces apoptosis of activated lamina propria T lymphocytes in patients with Crohn's disease in vitro. AIM: To test whether the ability of rapid anti‐TNF‐induced apoptosis in t...

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Detalhes bibliográficos
Main Authors: Van den Brande, Jan M H, Koehler, Tamara C, Zelinkova, Zuzana, Bennink, Roelof J, te Velde, Anje A, Cate, Fibo J W ten, van Deventer, Sander J H, Peppelenbosch, Maikel P, Hommes, Daniël W
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2007
Assuntos:
Colon
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1856870/
https://ncbi.nlm.nih.gov/pubmed/17082252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2006.105379
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