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Pharmacokinetics, protein binding, and extravascular distribution of ceftizoxime in normal subjects.

Thirteen normal subjects were given 2, 3, or 4 g of ceftizoxime intravenously in a prospective single-blinded study. Serum and urine concentrations were measured for 48 h. The beta-phase serum half-life ranged from 1.4 to 1.7 h. Approximately 100% of the agent was recovered unchanged in the urine ov...

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Publicado no:Antimicrob Agents Chemother
Principais autores: Peterson, L R, Gerding, D N, Van Etta, L L, Eckfeldt, J H, Larson, T A
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1982
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC185674/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6295270/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.22.5.878
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