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GITR modulates innate and adaptive mucosal immunity during the development of experimental colitis in mice
BACKGROUND: Uncontrolled T cell activation and abnormal function of the innate immune system against normal enteric bacterial flora play a critical part in the pathogenesis of inflammatory bowel disease (IBD). Therefore, pharmacological strategies directed to restore the normal responsiveness of the...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BMJ Group
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1856662/ https://ncbi.nlm.nih.gov/pubmed/16763055 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2006.091181 |
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