Systemic antibodies towards mucosal bacteria in ulcerative colitis and Crohn’s disease differentially activate the innate immune response

Background and aims: The mucosa in ulcerative colitis (UC) is replete with antibody producing plasma B cells and polymorphonuclear leucocytes (PMN). This combination of effector cells requires a crosslinking antigen to evoke an antibody driven PMN inflammatory response via their Fc receptors. The st...

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Bibliographic Details
Main Authors: Furrie, E, Macfarlane, S, Cummings, J H, Macfarlane, G T
Format: Artigo
Language:Inglês
Published: Copyright 2004 by Gut 2004
Subjects:
Inflammatory Bowel Disease
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1773925/
https://ncbi.nlm.nih.gov/pubmed/14684582
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