Increased expression of high mobility group box 1 (HMGB1) is associated with an elevated level of the antiapoptotic c‐IAP2 protein in human colon carcinomas

BACKGROUND: High mobility group box 1 (HMGB1) is a non‐histone chromosomal protein implicated in a variety of biologically important processes, including transcription, DNA repair, V(D)J recombination, differentiation, and development. Overexpression of HMGB1 inhibits apoptosis, arguing that the mol...

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Main Authors: Völp, K, Brezniceanu, M‐L, Bösser, S, Brabletz, T, Kirchner, T, Göttel, D, Joos, S, Zörnig, M
Formato: Artigo
Idioma:Inglês
Publicado: BMJ Group 2006
Assuntos:
Colon Cancer
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1856519/
https://ncbi.nlm.nih.gov/pubmed/16118352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2004.062729
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