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Elevated Levels of High-Mobility Group Box-1 (HMGB1) in Patients with Severe or Uncomplicated Plasmodium falciparum Malaria

Severe malaria is characterized by a massive release of proinflammatory cytokines in the context of sequestration of parasitized and normal red cells (RBCs). High-mobility group box 1 (HMGB1) is a DNA- and heparin-binding protein that also acts as a cytokine when released from cells in the extracell...

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Detalhes bibliográficos
Main Authors: Angeletti, Davide, Kiwuwa, Mpungu Steven, Byarugaba, Justus, Kironde, Fred, Wahlgren, Mats
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Tropical Medicine and Hygiene 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3617861/
https://ncbi.nlm.nih.gov/pubmed/23400574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4269/ajtmh.12-0530
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