In vivo imaging of cerebral “peripheral benzodiazepine binding sites” in patients with hepatic encephalopathy

BACKGROUND AND AIM: One proposed mechanism whereby hepatic encephalopathy (HE) leads to loss of brain function is dysregulated synthesis of neurosteroids. Mitochondrial synthesis of neurosteroids is regulated by “peripheral benzodiazepine binding sites” (PBBS). Expressed in the brain by activated gl...

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Main Authors: Cagnin, A, Taylor‐Robinson, S D, Forton, D M, Banati, R B
Format: Artigo
Jezik:Inglês
Izdano: BMJ Group 2006
Teme:
Liver Disease
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1856189/
https://ncbi.nlm.nih.gov/pubmed/16210399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2005.075051
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